Selected Research Articles on IBS, Food Allergies, and Related Issues

Top Articles - Great Research

Di Sabatino et. al. 2015. Small Amounts of Gluten in Subjects with Suspected Nonceliac Gluten Sensitivity: a Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial. Clin Gastroenterol Hepatol. 2015 Feb 19. pii: S1542-3565(15)00153-6. doi: 10.1016/j.cgh.2015.01.029. [Epub ahead of print]

Clayton et. al. 2014. Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE. Gastroenterology. 2014 Sep;147(3):602-9. doi: 10.1053/j.gastro.2014.05.036. Epub 2014 Jun 4.

Vojdani et. al. 2014. The Prevalence of Antibodies against Wheat and Milk Proteins in Blood Donors and Their Contribution to Neuroimmune Reactivities. Nutrients 2014, 6(1), 15-36; doi:10.3390/nu6010015

Cannistrà et. al. (2013). New perspectives in the treatment of hidradenitis suppurativa: surgery and brewer's yeast-exclusion diet. Surgery. 2013 Nov;154(5):1126-30. doi: 10.1016/j.surg.2013.04.018. Epub 2013 Jul 25.

Uzunismail et. al (2012). The effects of provocation by foods with raised IgG antibodies and additives on the course of Crohn's disease: a pilot study. Turk J Gastroenterol. 2012 Feb;23(1):19-27.[Full Text]

Carroccio et. al. (2012). Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity. Am J Gastroenterol. 2012 Jul 24. doi: 10.1038/ajg.2012.236. [Epub ahead of print]

Biesiekierski et. al. (2011). Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease: A Double-Blind Randomized Placebo-Controlled Trial. Am J Gastroenterol. 2011 Jan 11. [Epub ahead of print]

Sapone et. al. (2011). Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Med. 2011 Mar 9;9(1):23. [Epub ahead of print]

Alpay et. al. (2010). Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial. Cephalalgia. 2010 July; 30(7): 829–837.doi: 10.1177/0333102410361404. [Full Text]

Collins, et. al. (2009). The putative role of the intestinal microbiota in the irritable bowel syndrome. Dig Liver Dis. 2009 Sep 7. [Epub ahead of print]

Sverremark-Ekström et. a. (2012). Peanut sensitization during the first 5 yr of life is associated with elevated levels of peanut-specific IgG. Pediatr Allergy Immunol. 2012 May;23(3):224-9. doi: 10.1111/j.1399-3038.2012.01290.x.

Lui et. al. (2012). Characteristics of patients suffering from cow milk allergy. Int Immunopharmacol. 2012 Sep;14(1):94-8. doi: 10.1016/j.intimp.2012.06.008. Epub 2012 Jun 18.

Giovanna et. al. (2012). The immunopathogenesis of cow's milk protein allergy (CMPA). Ital J Pediatr. 2012 Jul 23;38:35. [Full Text]

Bernardi et. al. (2008). Time to reconsider the clinical value of immunoglobulin G4 to foods? Clin Chem Lab Med. 2008;46(5):687-90

Arroyave Hernández et. al. (2008). Food allergy mediated by IgG antibodies associated with migraine in adults. Rev Alerg Mex. 2007 Sep-Oct;54(5):162-8.

Drisko et. al.(2006). Treating Irritable Bowel Syndrome with a Food Elimination Diet Followed by Food Challenge and Probiotics. Journal of the American College of Nutrition, Vol. 25, No. 6, 514-522

Yang and Li (2007). [The therapeutic effects of eliminating allergic foods according to food-specific IgG antibodies in irritable bowel syndrome][Article in Chinese]. Zhonghua Nei Ke Za Zhi. 2007 Aug;46(8):641-3.

Hodsdon, W. and Zwickey, H. (2010). NMJ Original Research: Reproducibility and Reliability of Two Food Allergy Testing Methods. Natural Medicine Journal 2010 Mar.2(3):8-13

Ou-Yang, et. al. (2008). [Application of food allergens specific IgG antibody detection in chronic diarrhea in children.] [Article in Chinese]. Zhongguo Dang Dai Er Ke Za Zhi. 2008 Feb;10(1):21-4.

Vojdani, Aristo (2009). Detection of IgE, IgG, IgA and IgM antibodies against raw and processed food antigens. Nutr Metab (Lond). 2009; 6: 22. Published online 2009 May 12. [Full Text]

Hong et. al. (2009). Effect of probiotics on symptoms in korean adults with irritable bowel syndrome. Gut Liver. 2009 Jun;3(2):101-7. Epub 2009 Jun 30. [Full Text]

Ostblom et. al. (2007). Reported symptoms of food hypersensitivity and sensitization to common foods in 4-year-old children. Acta Paediatr. 2007 Dec 10 [Epub ahead of print].

Kiefte-de Jong et. al. (2010). Infant Nutritional Factors and Functional Constipation in Childhood: The Generation R Study. Am J Gastroenterol. 2010 Mar 2. [Epub ahead of print]

Zuo, et. al.(2007). Alterations of food antigen-specific serum immunoglobulins G and E antibodies in patients with irritable bowel syndrome and functional dyspepsia. Clinical & Experimental Allergy 37 (6), 823–830.

Wilders-Truschnig et. al. (2008). IgG antibodies against food antigens are correlated with inflammation and intima media thickness in obese juveniles. Exp Clin Endocrinol Diabetes. 2008 Apr;116(4):241-5. Epub 2007 Dec 10.

Kerckhoffs et. al. (2009). Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients. World J Gastroenterol. 2009 Jun 21;15(23):2887-92. [Full Text]

Lyra et. al. (2009). Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification. World J Gastroenterol 2009 December 21; 15(47): 5936-5945. [Full Text]

Parkes et. al. (2008). Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment. Am J Gastroenterol. 2008 Jun;103(6):1557-67. Epub 2008 May 29.

Borowiec and Fedorak. (2007). The role of probiotics in management of irritable bowel syndrome. Curr Gastroenterol Rep. 2007 Oct;9(5):393-400.

Collado et. al. (2007). Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol. 2007 Oct;45(4):454-60.

Rona et. al. (2007). The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol. 2007 Sep;120(3):638-46. Epub 2007 Jul 12.

Rayan et. al. (2007). Prevalence and clinical features of Dientamoeba fragilis infections in patients suspected to have intestinal parasitic infection. J Egypt Soc Parasitol. 2007 Aug;37(2):599-608.

Wang et. al. (2007). Potential non-immunoglobulin E-mediated food allergies: Comparison of open challenge and double-blind placebo-controlled food challenge. Otolaryngol Head Neck Surg. 2007 Nov;137(5):803-809.

Wahnschaffe et. al. (2007). Predictors of clinical response to gluten-free diet in patients diagnosed with diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2007 Jul;5(7):844-50. Epub 2007 Jun 5.

Stark et. al. (2006). Irritable bowel syndrome: A review on the role of intestinal protozoa and the importance of their detection and diagnosis. International Journal for Parasitology Volume 37, Issue 1, January 2007, Pages 11-20

Uz, et. al.(2007). Risk factors for irritable bowel syndrome in Turkish population: role of food allergy. J Clin Gastroenterol. 2007 Apr;41(4):380-3. (abstract only)

Cranney, et. al.(2007). The Canadian Celiac Health Survey. Dig Dis Sci. 2007 Apr;52(4):1087-95. Epub 2007 Feb 22

Grazioli, Barbara et. al.(2006). Giardia lamblia infection in patients with irritable bowel syndrome and dyspepsia: A prospective study. World Journal of Gastroenterology, World J Gastroenterol 2006 March 28; 12(12): 1941-1944

Wood, J.D. (2006). Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis,and food allergies. Gut 2006;55;445-447

Khan, W.I. and S.J. Collins (2006). Gut motor function: immunological control in enteric infection and inflammation. Clinical and Experimental Immunology 2006; 143:389–397

Zar et. al. (2005). Food-Specific Serum IgG4 and IgE Titers to Common Food Antigens in Irritable Bowel Syndrome. American Journal of Gastroenterology 2005; 100:1550-1557

Whorwell, P.J. et. al. (2006). Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. American Journal of Gastroenterology 2006 Jul;101(7):1581-90. (abstract only)

Shor et. al. (2009). Gluten sensitivity in multiple sclerosis: experimental myth or clinical truth? Ann N Y Acad Sci. 2009 Sep;1173:343-9.

Additional References

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Alverdy, JC and Chang, EB (2008). The re-emerging role of the intestinal microflora in critical illness and inflammation: why the gut hypothesis of sepsis syndrome will not go away. J Leukoc Biol. 2008 Mar;83(3):461-6. Epub 2007 Dec 26.

Amadi, B. (2002). Role of food antigen elimination in treating children with persistent diarrhea and malnutrition in Zambia. Journal of Pediatric Gastroenterology and Nutrition, 34(Suppl. 1), S54-S56.

Anthoni, et. al. (2009). Milk protein IgG and IgA: the association with milk-induced gastrointestinal symptoms in adults. World J Gastroenterol. 2009 Oct 21;15(39):4915-8. [Full Text]

Aragon et. al. (2010). Probiotic therapy for irritable bowel syndrome. Gastroenterol Hepatol (N Y). 2010 Jan;6(1):39-44. [Full Text]

Armisén et. al. (2008). [Eosinophilic esophagitis due to allergy to sheep and goat milk proteins] [Article in Spanish] Rev Esp Enferm Dig. 2008 Jan;100(1):53-6.

Armentia, A., Rodriguez, R., Callejo, A., Martin-Esteban, M., Martin-Santos, J. M., Salcedo, G., Pascual, C., Sanchez-Monge, R., & Pardo, M. (2002). Allergy after ingestion or inhalation of cereals involves similar allergens in different ages. Clinical and Experimental Allergy, 32(8), 1216-1222.

Armentia, A. (2008). Adverse reactions to wine: think outside the bottle. Curr Opin Allergy Clin Immunol. 2008 Jun;8(3):266-9.Click here to read

Arslan Leid, et. al. (2010). Intestinal B cell-activating factor (BAFF): an indicator of non-IgE-mediated hypersensitivity reactions to food? Aliment Pharmacol Ther. 2010 Mar 26. [Epub ahead of print]

Asero, et. al. (2009). Detection of a novel allergen in raw tomato. J Investig Allergol Clin Immunol. 2008;18(5):397-400.

Astegiano et. al (2008). 2008 Clinical approach to irritable bowel syndrome. Minerva Gastroenterol Dietol. 2008 Sep;54(3):251-8.

Atkinson et. al. (2004). Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut. 2004 October; 53(10): 1459–1464. [Full Text]

Attaluri, et. al. (2010). Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS. Am J Gastroenterol. 2010 Jun;105(6):1407-11. Epub 2009 Dec 1.

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Ballmer-Weber et. al. (2012). Component-resolved in vitro diagnosis of carrot allergy in three different regions of Europe. Allergy. 2012 Jun;67(6):758-66. doi: 10.1111/j.1398-9995.2012.02827.x. Epub 2012 Apr 10.

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Bascones, et. al. (2009). Lettuce-induced anaphylaxis. Identification of the allergen involved. J Investig Allergol Clin Immunol. 2009;19(2):154-7.

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Ben-Shoshan et. al. (2009). Is the prevalence of peanut allergy increasing? A 5-year follow-up study in children in Montreal. J Allergy Clin Immunol. 2009 Apr;123(4):783-8.

Bentz et. al. (2010). Clinical relevance of IgG antibodies against food antigens in Crohn's disease: a double-blind cross-over diet intervention study. Digestion. 2010;81(4):252-64. Epub 2010 Jan 30.

Berkner et. al. (2009). Cross-reactivity of pollen and food allergens: soybean Gly m 4 is a member of the Bet v 1 superfamily and closely resembles yellow lupine proteins. Biosci Rep. 2009 Jun;29(3):183-92.

Besu et. al. (2013) Good tolerance to goat's milk in patients with recurrent aphthous ulcers with increased immunoreactivity to cow's milk proteins. J Oral Pathol Med. 2013 Aug;42(7):523-7. doi: 10.1111/jop.12052. Epub 2013 Feb 25.

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Bischoff SC. (2010). Food allergy and eosinophilic gastroenteritis and colitis. Curr Opin Allergy Clin Immunol. 2010 Jun;10(3):238-45

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Bixquert Jiménez M. (2009). Treatment of irritable bowel syndrome with probiotics. An etiopathogenic approach at last? Rev Esp Enferm Dig. 2009 Aug;101(8):553-64.

Boirivant M, and Strober W. (2007). The mechanism of action of probiotics. Curr Opin Gastroenterol. 2007 Nov;23(6):679-92.

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Bouhnik et. al. (2007). Four-week short chain fructo-oligosaccharides ingestion leads to increasing fecal bifidobacteria and cholesterol excretion in healthy elderly volunteers. Nutr J. 2007 Dec 5;6:42.

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Brenner et. al. (2009). The utility of probiotics in the treatment of irritable bowel syndrome: a systematic review. Am J Gastroenterol. 2009 Apr;104(4):1033-49; quiz 1050. Epub 2009 Mar 10.

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Delchier, JC. (2008). [Gastrointestinal manifestations of Helicobacter pylori infection in adults: from gastritis to gastric cancer][Article in French] Presse Med. 2008 Mar;37(3 Pt 2):519-24. Epub 2008 Feb 7.

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Ducrotté P. (2010). [Microbiota and irritable bowel syndrome]. [Article in French] Gastroenterol Clin Biol. 2010 Sep;34 Suppl 1:S52-6.

du Toit et. al. (2010). Identifying and managing cow's milk protein allergy. Arch Dis Child Educ Pract Ed. 2010 Oct;95(5):134-44. Epub 2010 Aug 5.

Edwards George et. al. (2008). Psychological Correlates of Gluten-free Diet Adherence in Adults With Celiac Disease. J Clin Gastroenterol. 2008 Jun 17. [Epub ahead of print]

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